Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622953 | 0.92 | NPC1 (0.33) | NPC1ALDH1A1LMNA | |
| SCHEMBL27622959 | 0.79 | NPC1 (0.35) | NPC1HSD17B1HSD11B1HSD17B2ALDH1A1 | |
| SCHEMBL27564639 | 0.72 | HSD11B1 (0.55) | HSD17B1HSD11B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL27603880 | 0.72 | MEN1 (0.43) | NPC1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27622706 | 0.70 | KMT2A (0.37) | HSD17B1HSD11B1HSD17B2ALDH1A1LMNA | |
| SCHEMBL5830977 | 0.69 | HSD11B1 (0.44) | NPC1HSD17B1HSD11B1HSD17B2ALDH1A1 | |
| SCHEMBL27534024 | 0.69 | KMT2A (0.36) | NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL5832128 | 0.67 | AKT1 (0.47) | HSD17B1HSD11B1HSD17B2ALDH1A1 | |
| SCHEMBL27590773 | 0.67 | CA2 (0.32) | — | |
| SCHEMBL5831222 | 0.66 | USP36 (0.46) | NPC1HSD17B1HSD11B1HSD17B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | claimed |