Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16144662 | 0.84 | HIF1A (0.55) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Hydrochloric Acid SCHEMBL28888659 | 0.81 | ADRA1A (0.55) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL4713568 | 0.80 | ADRA1A (0.54) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL14465574 | 0.78 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL14153976 | 0.78 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL20690347 | 0.78 | HIF1A (0.56) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL5173040 | 0.78 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL4256893 | 0.78 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| Oxilofrine SCHEMBL147458 | 0.78 | ADRA1A (0.67) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 | |
| SCHEMBL2123890 | 0.76 | HIF1A (0.54) | HIF1AADRA1ASLC6A2OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100418944-C | Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof | KISSEI PHARMACEUTICAL (JP) | 2008-09-17 | — | — | CN | disclosed |
| CN-1751019-A | Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof | KISSEI PHARMACEUTICAL (JP) | 2006-03-22 | — | — | CN | disclosed |