Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28110877 | 0.99 | PPARA (0.49) | PPARACYSLTR2CYSLTR1EPHX2SOAT2 | |
| Sulfuric Acid SCHEMBL27996445 | 0.97 | PPARA (0.48) | PPARACYSLTR2CYSLTR1EPHX2SOAT2 | |
| Sulfuric Acid SCHEMBL27969762 | 0.96 | PPARA (0.47) | PPARACYSLTR2CYSLTR1EPHX2SOAT2 | |
| SCHEMBL28918162 | 0.91 | AOC3 (0.53) | PPARACYSLTR2CYSLTR1EPHX2SOAT2 | |
| SCHEMBL28154134 | 0.91 | AOC3 (0.53) | PPARACYSLTR2CYSLTR1EPHX2SOAT2 | |
| Ethylene SCHEMBL28818893 | 0.88 | AOC3 (0.50) | PPARACYSLTR2CYSLTR1EPHX2SOAT2 | |
| Sulfuric Acid SCHEMBL27676454 | 0.83 | LTA4H (0.48) | PPARAEPHX2FAAHCNR1LTA4H | |
| SCHEMBL11612744 | 0.83 | SOAT2 (0.51) | PPARACYSLTR2CYSLTR1EPHX2SOAT2 | |
| Sulfuric Acid SCHEMBL28135054 | 0.80 | AOC3 (0.51) | PPARAAOC3PPARGLTA4H | |
| SCHEMBL7166673 | 0.80 | TP53 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1715228-A | Glass fiber binder composition and glass fiber mat | NISHIN CHEMICAL INDUSTRY CO LT (JP) | 2006-01-04 | — | — | CN | disclosed |