SCHEMBL27623637

SCHEMBL27623637

C=C(C)C(=O)Nc1c2ccccc2cc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 5/20 0.43
HPGD P15428 4/20 0.43
KMT2A Q03164 4/20 0.43
KDM4E B2RXH2 3/20 0.43
GLA P06280 2/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 1/20 0.41
ABCC9 O60706 1/20 0.40
ABCC8 Q09428 1/20 0.40
KCNJ11 Q14654 1/20 0.40
KCNJ8 Q15842 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28230915 0.87 TDP1 (0.38) TDP1ALDH1A1HPGDKMT2AKDM4E
SCHEMBL28249202 0.86 TDP1 (0.37) TDP1ALDH1A1HPGDKMT2AKDM4E
SCHEMBL13588237 0.82 ALDH1A1 (0.46) TDP1ALDH1A1HPGDKMT2AKDM4E
SCHEMBL3820869 0.82 G6PD (0.50) TDP1ALDH1A1HPGDKMT2AKDM4E
SCHEMBL8899556 0.82 ABCC9 (0.55) ALDH1A1HPGDKMT2AKDM4EGLA
SCHEMBL13134235 0.81 KDM4E (0.55) ALDH1A1HPGDKMT2AKDM4EGLA
SCHEMBL13609731 0.80 ALDH1A1 (0.53) TDP1ALDH1A1HPGDKMT2AKDM4E
SCHEMBL30473469 0.79 KMT2A (0.54) TDP1ALDH1A1KMT2AKDM4EMEN1
SCHEMBL329974 0.79 KMT2A (0.54) TDP1ALDH1A1KMT2AKDM4EMEN1
SCHEMBL10040374 0.78 CDC25B (0.50) TDP1ALDH1A1HPGDKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109471331-A Resin combination, photosensitive polymer combination, resin cured film and image-displaying member 昭和电工株式会社 2019-03-15 CN disclosed
CN-107108769-B Resin combination, colored filter, its manufacturing method and image-displaying member 昭和电工株式会社 2019-02-19 CN disclosed
CN-108713031-A The manufacturing method of random copolymer, anti-corrosion agent composition, colour filter and random copolymer DIC株式会社 2018-10-26 CN disclosed
CN-102584617-B Fluorescent indicator containing condensed-ring methacrylamide and applications of fluorescent indicator to be taken as fluorescent probe UNIV HANGZHOU NORMAL 2014-04-09 CN disclosed
CN-102584617-A Fluorescent indicator containing condensed-ring methacrylamide and applications of fluorescent indicator to be taken as fluorescent probe UNIV HANGZHOU NORMAL 2012-07-18 CN disclosed
CN-1902550-B Composition for forming nitride coating film for hard mask NISSAN CHEMICAL IND LTD 2012-07-18 CN disclosed
CN-100585496-C Sulfur-atom-containing composition for forming lithographic antireflection film NISSAN CHEMICAL IND LTD 2010-01-27 CN disclosed
CN-101040220-A Sulfur-atom-containing composition for forming of lithographic antireflection film NISSAN CHEMICAL IND LTD (JP) 2007-09-19 CN disclosed
CN-1918515-A Curable resin composition, color filter and liquid crystal display device MITSUBISHI CHEM CORP (JP) 2007-02-21 CN disclosed
CN-1902550-A Composition for forming nitride coating film for hard mask NISSAN CHEMICAL IND LTD (JP) 2007-01-24 CN disclosed
CN-1790772-A Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORP (JP) 2006-06-21 CN disclosed
CN-1713787-A Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORP (JP) 2005-12-28 CN disclosed