SCHEMBL276242

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL277051	0.81	PELI1 (0.50)	ESR1ESR2ERN1ACMSDPELI1
	SCHEMBL649501	0.73	ALDH1A1 (0.54)	ESR2ERN1ACMSDPELI1TMIGD3
	SCHEMBL6599324	0.73	ESR1 (0.41)	ESR1ESR2ERN1ACMSDCYP2A6
	SCHEMBL2094304	0.71	CYP2A6 (0.50)	ESR1ESR2CYP2A6CYP2E1CYP2B6
	SCHEMBL2009274	0.71	KCNH2 (0.57)	ESR1ESR2CYP2A6CYP2E1CYP2B6
	SCHEMBL1378848	0.71	PELI1 (0.54)	ERN1ACMSDPELI1TMIGD3ADORA2A
	Hydrochloric Acid SCHEMBL30870502	0.71	ALDH1A1 (0.52)	ESR2ERN1ACMSDPELI1TMIGD3
	SCHEMBL28764322	0.71	ALDH1A1 (0.52)	ESR2ERN1ACMSDPELI1TMIGD3
	Hydrochloric Acid SCHEMBL6287793	0.70	PELI1 (0.53)	ERN1ACMSDPELI1TMIGD3ADORA2A
	SCHEMBL1761885	0.70	ACMSD (0.54)	ESR1ESR2ACMSDCYP2A6CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.