Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753710 | 0.86 | ALDH1A1 (0.50) | DHFRTDP1GRM5ALPGL3MBTL1 | |
| SCHEMBL424974 | 0.83 | DHFR (0.46) | DHFRTDP1GRM5ALPGL3MBTL1 | |
| SCHEMBL10904140 | 0.83 | DHFR (0.43) | DHFRTDP1GRM5ALPGL3MBTL1 | |
| SCHEMBL30417871 | 0.81 | DHFR (0.45) | DHFRTDP1GRM5MAOBALDH1A1 | |
| SCHEMBL5043256 | 0.80 | KIF11 (0.49) | DHFRTDP1GRM5ALPGL3MBTL1 | |
| SCHEMBL11841971 | 0.79 | TDP1 (0.44) | DHFRTDP1GRM5ALPGL3MBTL1 | |
| SCHEMBL19692896 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPK1 | |
| SCHEMBL5637889 | 0.79 | HTR1A (0.43) | MAOBALDH1A1DRD2DRD3SLC6A2 | |
| SCHEMBL29650290 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPK1 | |
| SCHEMBL9560135 | 0.79 | TSHR (0.41) | DHFRTDP1MAOBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1671386-A | Substituted anilinic piperidines as MCH selective antagonists | LUNDBECK & CO AS H (DK) | 2005-09-21 | — | — | CN | disclosed |