Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607823 | 0.83 | ESR2 (0.41) | SRCCHRM1ADRA1AHTR2B | |
| SCHEMBL27549906 | 0.78 | ESR1 (0.41) | MEN1KMT2ALMNACHRM1SLC6A2 | |
| SCHEMBL28017568 | 0.77 | HTR1A (0.40) | SLC6A2TDP1ALDH1A1 | |
| SCHEMBL3413433 | 0.76 | TDP1 (0.35) | SRCCASRMEN1KMT2ATRPA1 | |
| SCHEMBL27546845 | 0.73 | CYP2A6 (0.38) | MEN1KMT2ALMNATDP1SMN1; SMN2 | |
| SCHEMBL27766137 | 0.73 | TRPA1 (0.41) | SRCCASRTRPA1LMNACHRM1 | |
| SCHEMBL27624254 | 0.72 | MEN1 (0.31) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27624261 | 0.72 | CYP3A4 (0.36) | LMNAHTR2BTP53TDP1SMN1; SMN2 | |
| SCHEMBL27605513 | 0.71 | ACP3 (0.40) | TP53TDP1HTTALDH1A1 | |
| SCHEMBL27626730 | 0.71 | SMN1; SMN2 (0.40) | SRCMEN1KMT2ATRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611005-A | Be used as the acetophenones of the replacement of PDE4 inhibitor | LEO PHARMA AS (DK) | 2009-12-23 | — | — | CN | disclosed |
| CN-100381429-C | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2008-04-16 | — | — | CN | disclosed |
| CN-1946703-A | Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators | TRANSTECH PHARMA INC (US) | 2007-04-11 | — | — | CN | disclosed |
| CN-1675188-A | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2005-09-28 | — | — | CN | disclosed |