Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.62 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646618 | 0.94 | PLAU (0.60) | MAPTL3MBTL1SRD5A2STSPLAU | |
| SCHEMBL7129800 | 0.88 | MAPT (0.80) | MAPTL3MBTL1SRD5A2STSPLAU | |
| SCHEMBL27625881 | 0.85 | LOXL2 (0.51) | MAPTL3MBTL1SRD5A2STSPLAU | |
| SCHEMBL11635179 | 0.84 | L3MBTL1 (0.69) | MAPTL3MBTL1SRD5A2STSPLAU | |
| Hydrochloric Acid SCHEMBL27462374 | 0.84 | LOXL2 (0.50) | MAPTL3MBTL1SRD5A2STSPLAU | |
| Hydrochloric Acid SCHEMBL27462372 | 0.84 | LOXL2 (0.54) | MAPTL3MBTL1SRD5A2STSPLAU | |
| SCHEMBL24800 | 0.83 | MAPT (0.73) | MAPTL3MBTL1SRD5A2STSPLAU | |
| SCHEMBL7199268 | 0.83 | MAPT (0.67) | MAPTL3MBTL1SRD5A2STSPLAU | |
| SCHEMBL13256390 | 0.83 | RAB9A (0.71) | MAPTL3MBTL1SRD5A2LOXL2RAB9A | |
| SCHEMBL2755181 | 0.82 | L3MBTL1 (0.67) | MAPTL3MBTL1SRD5A2STSPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |