Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11994151 | 0.87 | SLC6A4 (0.58) | SLC6A4SLC6A3TUBB4ATUBBTUBA3C | |
| SCHEMBL30505632 | 0.85 | BCAT2 (0.57) | LTB4R2MAPTSMN1; SMN2PDK2L3MBTL1 | |
| SCHEMBL3420505 | 0.85 | BCAT2 (0.57) | LTB4R2MAPTSMN1; SMN2PDK2L3MBTL1 | |
| SCHEMBL9542216 | 0.84 | L3MBTL1 (0.46) | SLC6A4SLC6A3LTB4R2MAPTSMN1; SMN2 | |
| SCHEMBL9125028 | 0.84 | HSP90AB1 (0.49) | SLC6A4SLC6A3LTB4R2MAPTSMN1; SMN2 | |
| SCHEMBL27539512 | 0.84 | BCAT2 (0.55) | LTB4R2MAPTSMN1; SMN2PDK2L3MBTL1 | |
| SCHEMBL28693105 | 0.83 | BCAT2 (0.46) | SLC6A4SLC6A3LTB4R2MAPTSMN1; SMN2 | |
| SCHEMBL27481642 | 0.83 | CHRNA7 (0.45) | SLC6A4SLC6A3LTB4R2MAPTSMN1; SMN2 | |
| SCHEMBL847199 | 0.83 | SLC6A3 (0.59) | SLC6A4SLC6A3LTB4R2MAPTSMN1; SMN2 | |
| SCHEMBL28116436 | 0.83 | LTB4R2 (0.49) | SLC6A4SLC6A3LTB4R2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102292321-B | Pyrazolyl-substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor for the treatment of receptor-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2015-08-12 | — | — | CN | disclosed |
| CN-102292321-A | Pyrazolyl-substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor for the treatment of receptor-related disorders | — | 2011-12-21 | — | — | CN | disclosed |
| CN-101454299-A | Ureide derivative and use thereof for medical purposes | TORAY INDUSTRIES (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-100357282-C | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CJ CORP (KR) | 2007-12-26 | — | — | CN | disclosed |
| CN-1705650-A | Isothiazole derivatives, process for preparing the same, and pharmaceutical composition comprising the same | CJ CORP (KR) | 2005-12-07 | — | — | CN | disclosed |