Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420505 | 0.85 | BCAT2 (0.57) | SMN1; SMN2MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL30505632 | 0.85 | BCAT2 (0.57) | SMN1; SMN2MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9125028 | 0.84 | HSP90AB1 (0.49) | SLC6A3SMN1; SMN2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9542216 | 0.84 | L3MBTL1 (0.46) | SLC6A3SMN1; SMN2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL27539512 | 0.84 | BCAT2 (0.55) | SMN1; SMN2MAPTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL27628186 | 0.83 | SLC6A4 (0.61) | SLC6A3SMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL28116436 | 0.83 | LTB4R2 (0.49) | SLC6A3SMN1; SMN2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL28693105 | 0.83 | BCAT2 (0.46) | SLC6A3SMN1; SMN2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7536487 | 0.83 | SLC6A4 (0.61) | SLC6A3SMN1; SMN2MAPTL3MBTL1MEN1 | |
| SCHEMBL28837363 | 0.82 | ALDH1A1 (0.50) | SLC6A3SMN1; SMN2MAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106547168-A | A kind of black-matrix material compositionss and application | 深圳市华星光电技术有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-101374515-B | Inhibitors of akt activity | MERCK SHARP & DOHME | 2013-01-09 | — | — | CN | disclosed |
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | disclosed |
| CN-101374515-A | Inhibitors of AKT activity | MERCK & CO INC (US) | 2009-02-25 | — | — | CN | disclosed |
| CN-100357282-C | Isothiazole derivatives, process for the preparation thereof, and pharmaceutical composition including the same | CJ CORP (KR) | 2007-12-26 | — | — | CN | disclosed |
| CN-1705650-A | Isothiazole derivatives, process for preparing the same, and pharmaceutical composition comprising the same | CJ CORP (KR) | 2005-12-07 | — | — | CN | disclosed |