SCHEMBL27628657

SCHEMBL27628657

CN1C(C)(C)CC(NC(=O)c2ccc(N)cc2)CC1(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
KDM4E B2RXH2 2/20 0.53
GAA P10253 2/20 0.53
MAOB P27338 1/20 0.47
EZH2 Q15910 3/20 0.47
POLB P06746 2/20 0.46
DDB1 Q16531 1/20 0.44
CRBN Q96SW2 1/20 0.44
IKZF3 Q9UKT9 1/20 0.44
GLA P06280 1/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 1/20 0.41
ESR1 P03372 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPC1 O15118 1/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1414505 0.86 HDAC4 (0.53) HDAC4HDAC6KDM4EGAAMAOB
SCHEMBL4977116 0.85 EZH2 (0.59) HDAC4HDAC6KDM4EGAAMAOB
SCHEMBL9456941 0.84 HDAC4 (0.57) HDAC4HDAC6KDM4EGAAMAOB
SCHEMBL27800113 0.83 MEN1 (0.50) HDAC4HDAC6KDM4EGAAEZH2
SCHEMBL27636094 0.81 EZH2 (0.70) EZH2POLBGLAKMT2AMEN1
SCHEMBL12825891 0.80 PKM (0.50) HDAC4HDAC6KDM4EGAAEZH2
SCHEMBL27800057 0.77 KMT2A (0.46) HDAC4HDAC6KDM4EGAACRBN
SCHEMBL1202785 0.77 SLC6A5 (0.54) HDAC4HDAC6KMT2AMEN1ALDH1A1
SCHEMBL5766004 0.76 HDAC4 (0.47) HDAC4HDAC6KDM4EGAAMAOB
SCHEMBL3442327 0.76 RAB9A (0.62) MAOBPOLBDDB1CRBNIKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101914300-B X-type active light-resistant orange azo dye and preparation method thereof UNIV QINGDAO 2013-10-30 CN claimed
CN-101899225-B X-type active light-resistant red azo dye and preparation method thereof UNIV QINGDAO 2013-07-17 CN claimed
CN-101914300-B X-type active light-resistant orange azo dye and preparation method thereof UNIV QINGDAO 2013-10-30 CN disclosed
CN-101899225-B X-type active light-resistant red azo dye and preparation method thereof UNIV QINGDAO 2013-07-17 CN disclosed
CN-101948631-A K type reactive light-resistant orange azo dye and preparation method thereof UNIV QINGDAO 2011-01-19 CN disclosed
CN-101914300-A X-type active light-resistant orange azo dye and preparation method thereof UNIV QINGDAO 2010-12-15 CN disclosed
CN-101914302-A K-type active light-resistant red azo dye and preparation method thereof UNIV QINGDAO 2010-12-15 CN disclosed
CN-101899225-A X-type active light-resistant red azo dye and preparation method thereof UNIV QINGDAO 2010-12-01 CN disclosed
CN-100371394-C Light resistant, bis-azo yellow organic pigment and method for preparing the same UNIV QINGDAO (CN) 2008-02-27 CN disclosed
CN-100371393-C Light resistant, mono azo organic yellow pigment and method for preparing the same UNIV QINGDAO (CN) 2008-02-27 CN disclosed
CN-1803932-A Light resistant, bis-azo yellow organic pigment and method for preparing the same UNIV QINGDAO (CN) 2006-07-19 CN disclosed
CN-1803930-A Photooxidation resistant red azo organic pigment and method for preparing the same UNIV QINGDAO (CN) 2006-07-19 CN disclosed
CN-1803929-A Light resistant, mono azo organic yellow pigment and method for preparing the same UNIV QINGDAO (CN) 2006-07-19 CN disclosed