Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 13/20 | 0.46 |
| ▸ | F13A1 | P00488 | 10/20 | 0.46 |
| ▸ | TGM1 | P22735 | 8/20 | 0.46 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936042 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL5000197 | 0.75 | GPR119 (0.48) | TGM2F13A1TGM1GPR119POLB | |
| SCHEMBL27648986 | 0.73 | USP2 (0.52) | TGM2F13A1TGM1TGM3GPR119 | |
| SCHEMBL948376 | 0.71 | GPR119 (0.49) | GPR119 | |
| Trifluoromethanesulfonic Acid SCHEMBL5003105 | 0.70 | GPR119 (0.43) | TGM2F13A1TGM1GPR119POLB | |
| SCHEMBL2253614 | 0.69 | USP2 (0.49) | TGM2F13A1TGM1GPR119STS | |
| SCHEMBL948139 | 0.68 | GPR119 (0.53) | GPR119 | |
| SCHEMBL27293234 | 0.67 | TGM2 (0.52) | TGM2F13A1TGM1TGM3STS | |
| SCHEMBL9285414 | 0.66 | GPR119 (0.49) | TGM2F13A1TGM1TGM3GPR119 | |
| SCHEMBL11945569 | 0.65 | TGM2 (0.49) | TGM2F13A1TGM1TGM3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100465163-C | Cis-2,4,5-triaryl-imidazolines | HOFFMANN LA ROCHE (CH) | 2009-03-04 | — | — | CN | disclosed |
| CN-1809538-A | Cis-2,4,5-triaryl-imidazolines | HOFFMANN LA ROCHE (CH) | 2006-07-26 | — | — | CN | disclosed |