Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111759 | 0.78 | CHAT (0.39) | PTGER4PTGER3PTGER2 | |
| SCHEMBL4722670 | 0.78 | NFE2L2 (0.34) | PTGER4PTGER3PTGER2NFE2L2 | |
| SCHEMBL9111761 | 0.78 | CHAT (0.39) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6725286 | 0.78 | PNMT (0.41) | PNMTDPP4LOXL2PTGER4PTGER3 | |
| SCHEMBL18193098 | 0.78 | PNMT (0.41) | PNMTDPP4LOXL2PTGER4PTGER3 | |
| SCHEMBL7959778 | 0.78 | PNMT (0.41) | PNMTDPP4LOXL2PTGER4PTGER3 | |
| SCHEMBL7959776 | 0.78 | PNMT (0.41) | PNMTDPP4LOXL2PTGER4PTGER3 | |
| SCHEMBL263092 | 0.77 | PNMT (0.44) | PNMTDPP4LOXL2KDM4ESMN1; SMN2 | |
| SCHEMBL20124829 | 0.77 | NFE2L2 (0.50) | PNMTDPP4PTGER4PTGER3PTGER2 | |
| SCHEMBL1248288 | 0.77 | NFE2L2 (0.50) | PNMTDPP4PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-101657414-A | Oxime compound, photosensitive composition, color filter, method for production of the color filter, and liquid crystal display element | FUJIFILM CORP JP | 2010-02-24 | — | — | CN | disclosed |
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |