Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 7/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063331 | 0.72 | CA1 (0.35) | CA1CA2CA12CA9CA14 | |
| SCHEMBL28300983 | 0.69 | CA9 (0.53) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL4603369 | 0.68 | TDP1 (0.58) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL1130962 | 0.68 | VCAM1 (0.53) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL1185703 | 0.68 | VCAM1 (0.49) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL6812640 | 0.67 | TDP1 (0.52) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL3868816 | 0.67 | ALDH1A1 (0.37) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL19071926 | 0.66 | ALDH1A1 (0.55) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL19071931 | 0.66 | L3MBTL1 (0.50) | VCAM1CA1CA2CA12CA9 | |
| SCHEMBL4607518 | 0.66 | VCAM1 (0.54) | VCAM1CA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100363368-C | thiadiazine derivatives and their use as positive AMPA receptor modulators | SERVIER LAB (FR) | 2008-01-23 | — | — | CN | disclosed |
| CN-1798750-A | Thiadiazine derivatives and use thereof as positive ampa receptor modulators | SERVIER LAB (FR) | 2006-07-05 | — | — | CN | disclosed |