Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639804 | 0.83 | LMNA (0.47) | TDP1LMNAMTNR1AMTNR1BGPR88 | |
| SCHEMBL28126891 | 0.80 | TDP1 (0.69) | TDP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL28821943 | 0.79 | LMNA (0.47) | TDP1LMNAMTNR1AMTNR1BGPR88 | |
| SCHEMBL27811283 | 0.79 | TDP1 (0.58) | TDP1MEN1KMT2ANPC1MAPT | |
| SCHEMBL10654885 | 0.79 | TDP1 (0.58) | TDP1MEN1KMT2ANPC1MAPT | |
| SCHEMBL27831584 | 0.78 | TDP1 (0.56) | TDP1MEN1KMT2ANPC1MAPT | |
| SCHEMBL10676882 | 0.78 | TDP1 (0.56) | TDP1MEN1KMT2ANPC1MAPT | |
| SCHEMBL27629503 | 0.77 | MEN1 (0.43) | TDP1MEN1KMT2ANPC1MAPT | |
| SCHEMBL6718126 | 0.76 | L3MBTL1 (0.61) | LMNAL3MBTL1 | |
| SCHEMBL4550642 | 0.76 | ALOX5 (0.53) | TDP1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |