Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | PTGES | O14684 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966237 | 0.95 | ALOX5 (0.49) | ALOX5PPARGPPARAPTGESTDP1 | |
| 2-Ethylhexanoic Acid SCHEMBL3847865 | 0.86 | LMNA (0.59) | ALOX5PPARGPPARAPTGESMAPK1 | |
| SCHEMBL21896388 | 0.84 | KDM4E (0.49) | ALOX5PPARGPTGESKMT2A | |
| SCHEMBL21896387 | 0.84 | KDM4E (0.49) | ALOX5PPARGPTGESKMT2A | |
| SCHEMBL5514903 | 0.84 | TBXA2R (0.47) | PPARGPPARALMNAALDH1A1MTNR1A | |
| SCHEMBL5819286 | 0.83 | PLA2G4B (0.47) | TDP1MTNR1AMTNR1B | |
| SCHEMBL11052073 | 0.83 | LMNA (0.53) | PPARGPPARATDP1LMNAMTNR1A | |
| SCHEMBL5508346 | 0.83 | TBXA2R (0.49) | PPARGPPARALMNAMEN1ALDH1A1 | |
| Ethane SCHEMBL5531789 | 0.82 | LMNA (0.49) | PPARGPPARATDP1LMNAALDH1A1 | |
| SCHEMBL5515375 | 0.81 | TDP1 (0.59) | ALOX5PPARGPPARAPTGESTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |