Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 0.49 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.49 |
| ▸ | PDXK | O00764 | 1/20 | 0.49 |
| ▸ | GAK | O14976 | 1/20 | 0.49 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612430 | 0.91 | ADORA2A (0.47) | ADORA2AADORA1ADORA2BPIK3CGPIK3CA | |
| SCHEMBL27631997 | 0.89 | ADORA2A (0.46) | ADORA2AADORA1ADORA2BPIK3CGPIK3CA | |
| SCHEMBL1116418 | 0.88 | PIK3CG (0.60) | ADORA2AADORA1ADORA2BPIK3CGPIK3CA | |
| SCHEMBL27631996 | 0.82 | DCPS (0.48) | ADORA2AADORA1ADORA2BPIK3CGPIK3CA | |
| SCHEMBL27612968 | 0.79 | PIK3CG (0.50) | ADORA2AADORA1ADORA2BPIK3CGPIK3CA | |
| SCHEMBL27631757 | 0.76 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BPIK3CGCLK4 | |
| SCHEMBL27612323 | 0.76 | CSNK1A1 (0.55) | ADORA2AADORA1ADORA2BPIK3CGCLK4 | |
| SCHEMBL27631682 | 0.76 | ADORA1 (0.61) | ADORA2AADORA1ADORA2BPIK3CGPIK3CA | |
| SCHEMBL27716588 | 0.74 | CSNK1A1 (0.53) | ADORA2AADORA1ADORA2BPIK3CGCLK4 | |
| SCHEMBL688714 | 0.74 | ALDH1A1 (0.58) | ADORA1FLT3CSNK1DDYRK1ABRSK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |