Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.44 |
| ▸ | PDXK | O00764 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.44 |
| ▸ | STK16 | O75716 | 1/20 | 0.44 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | OXSR1 | O95747 | 1/20 | 0.44 |
| ▸ | LATS1 | O95835 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631865 | 0.89 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BPIK3CDPIK3CA | |
| SCHEMBL27612430 | 0.87 | ADORA2A (0.47) | ADORA2AADORA1ADORA2BPIK3CDPIK3CA | |
| SCHEMBL1116418 | 0.82 | PIK3CG (0.60) | ADORA2AADORA1ADORA2BPIK3CDPIK3CA | |
| SCHEMBL27631994 | 0.77 | DHFR (0.50) | ADORA2AADORA1ADORA2BPIK3CDPIK3CA | |
| SCHEMBL27631996 | 0.76 | DCPS (0.48) | ADORA2AADORA1ADORA2BPIK3CDPIK3CA | |
| SCHEMBL3791228 | 0.74 | ALDH1A1 (0.56) | MTORCSNK1A1CLK4DYRK1BFYN | |
| SCHEMBL27612968 | 0.73 | PIK3CG (0.50) | ADORA2AADORA1ADORA2BPIK3CDPIK3CA | |
| SCHEMBL27631918 | 0.72 | PIK3CG (0.64) | ADORA2AADORA1ADORA2BPIK3CDPIK3CA | |
| SCHEMBL27631757 | 0.71 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BPIK3CGMTOR | |
| SCHEMBL27612323 | 0.71 | CSNK1A1 (0.55) | ADORA2AADORA1ADORA2BPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |