Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 10/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | GRK5 | P34947 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779452 | 0.84 | HSD17B1 (0.64) | ALDH1A1HSD17B10HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL5162068 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CYP3A4MAP4K4LIMK1 | |
| Phenol SCHEMBL27847435 | 0.83 | ALDH1A1 (0.77) | ALDH1A1HSD17B10ADORA1L3MBTL1CA12 | |
| SCHEMBL3680161 | 0.82 | HSD17B1 (0.61) | ALDH1A1HSD17B10HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL17051267 | 0.80 | HSD17B1 (0.58) | ALDH1A1HSD17B10HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL5050883 | 0.80 | HSD17B1 (0.58) | ALDH1A1HSD17B10HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL6011365 | 0.80 | CA12 (0.54) | ALDH1A1HSD17B10HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL6573001 | 0.80 | CA12 (0.54) | ALDH1A1HSD17B10HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL27787239 | 0.79 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP3A4MAP4K4FGFR1 | |
| SCHEMBL30685324 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP3A4PLK4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114540-B | 1-hexyl-1H-pyrazoles-4,5-diamidogen Hemisulphate and the purposes in colouring compositions thereof | 宝洁公司 | 2016-06-22 | — | — | CN | claimed |
| CN-104114540-A | 1-HEXYL-1H-PYRAZOLE-4,5-DIAMINE HEMISULFATE, AND ITS USE IN DYEING COMPOSITIONS | PROCTER & GAMBLE | 2014-10-22 | — | — | CN | claimed |
| EP-3609468-A1 | METHOD FOR TREATING HAIR, KIT, AND USE OF THE KIT | Coty Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| CN-110267711-A | Method and kit for hair dyeing | 诺赛尔股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110200836-A | Hair colourant compositions, method and the box set comprising the composition | 诺赛尔股份有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-109661685-A | Calculate the composition for handling the preparation of hair fiber | 宝洁公司 | 2019-04-19 | — | — | CN | disclosed |
| WO-2018191362-A1 | METHOD FOR TREATING HAIR, KIT, AND USE OF THE KIT | COTY INC. (US) | 2018-10-18 | — | — | WO | disclosed |
| CN-107750154-A | Composition for dyeing hair using cationic direct dyes | 诺赛尔股份有限公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-107635536-A | Method for dyeing hair using direct dye compounds | 诺赛尔股份有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107635537-A | Composition for dyeing hair using cationic direct dyes | 诺赛尔股份有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-104168876-B | Hair colourant compositions, method and the box set for including the composition comprising the xylenol of 3 amino 2,6 and 1,4 paraphenylene diamine type developers | 诺赛尔股份有限公司 | 2017-11-03 | — | — | CN | disclosed |
| WO-2006023436-A1 | HAIR DYEING COMPOSITIONS COMPRISING 2-(AMINO OR SUBSTITUTED AMINO)-3-5-SUBSTITUTED PHENOL COMPOUNDS AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| WO-2006023435-A1 | 2-(AMINO OR SUBSTITUTED AMINO)-5, 6-SUBSTITUTED PHENOL COMPOUNDS, DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060032002-A1 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | PROCTER & GAMBLE COMPANY, THE | 2006-02-16 | — | — | US | disclosed |
| US-20060032001-A1 | 2-(Amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2006-02-16 | — | — | US | disclosed |
| US-20060032000-A1 | 2-(Amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY | 2006-02-16 | — | — | US | disclosed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| CN-1539816-A | IL-8 receptor antagonists | ʷ��˿�������ȳ�ķ����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1355697-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1215990-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-05-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060032001-A1 | 2-(Amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof | KRT18, S100A6, S100A4 | ALDH1A1 403/4885HSD17B10 2072/4885HSD17B1 3229/4885 |
| US-20060032002-A1 | Hair dyeing compositions comprising 2-(amino or substituted amino)-3-5-substituted phenol compounds and use thereof | KRT18, TYR, TH | ALDH1A1 247/4885HSD17B10 534/4885HSD17B1 799/4885 |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | ALDH1A1 131/4885HSD17B10 913/4885HSD17B1 1279/4885 |
| US-20060032000-A1 | 2-(Amino or substituted amino)-3-5-6-substituted phenol compounds, dyeing compositions containing them, and use thereof | KRT18, S100A6, S100A4 | ALDH1A1 459/4885HSD17B10 2382/4885HSD17B1 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.