Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15679211 | 0.78 | HTR2C (0.44) | HTR2AHTR2CHTR2BHRH3ADRA1A | |
| SCHEMBL4276600 | 0.78 | ADRA1A (0.40) | HTR2AHTR2CHTR2BHRH3ADRA1A | |
| SCHEMBL11471397 | 0.78 | TAS1R3 (0.40) | HTR2AHTR2CHTR2BHRH3GAA | |
| SCHEMBL11471398 | 0.78 | ALDH1A1 (0.39) | HTR2AHTR2CHTR2BHRH3TAS1R3 | |
| SCHEMBL5709417 | 0.77 | PRCP (0.56) | HTR2AHTR2CHTR2BHRH3SIGMAR1 | |
| SCHEMBL5709376 | 0.77 | SLC6A2 (0.60) | HTR2AHTR2CHTR2BHRH3ADRA1A | |
| SCHEMBL16212102 | 0.76 | TP53 (0.47) | HTR2AHTR2CHTR2BHRH3GAA | |
| SCHEMBL8849605 | 0.76 | DDB1 (0.53) | HTR2AHTR2CHTR2BHRH3ADRA1A | |
| SCHEMBL5710152 | 0.76 | PIN1 (0.51) | ADRA1AIDO1PDPK1SIGMAR1TAS1R3 | |
| SCHEMBL2984209 | 0.76 | IDO1 (0.48) | HTR2AADRA1AIDO1PDPK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103209949-B | Halogenated indenones and process for producing optically active indanones or optically active indanols using the same | 株式会社钟化 | 2016-08-10 | — | — | CN | disclosed |
| CN-104496780-A | Halogenated Indenones And Method For Producing Optically Active Indanones Or Optically Active Indanols By Using Same | KANEKA CORP | 2015-04-08 | — | — | CN | disclosed |
| CN-101119983-B | Crystalline base of trans-1-((1r,3s)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine | LUNDBECK & CO AS H | 2014-11-12 | — | — | CN | disclosed |
| CN-103429577-A | Method for resolution of 4-((1R,3S)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and 1-((1R,3S)-6-chloro-3-phenyl-indan, 1-yl)-3,3-dimethyl-piperazine | LUNDBECK & CO AS H | 2013-12-04 | — | — | CN | disclosed |
| CN-103209949-A | Halogenated indenones and process for producing optically active indanones or optically active indanols using the same | KANEKA CORP | 2013-07-17 | — | — | CN | disclosed |
| CN-101137632-B | Process for the preparation of trans-1- ((1R,3S) -6-chloro-3-phenylindan-1-yl) -3, 3-dimethylpiperazine | LUNDBECK & CO AS H | 2013-06-19 | — | — | CN | disclosed |
| CN-1835938-A | Trans-1(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine | LUNDBECK & CO AS H (DK) | 2006-09-20 | — | — | CN | disclosed |