Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371885 | 0.79 | L3MBTL1 (0.48) | MAPTALDH1A1POLBCA2CHKA | |
| SCHEMBL6195936 | 0.77 | L3MBTL1 (0.46) | MAPTALDH1A1POLBCA2CHKA | |
| SCHEMBL2415282 | 0.77 | MEN1 (0.33) | CA2CHKA | |
| SCHEMBL31093101 | 0.74 | — | — | |
| SCHEMBL18432567 | 0.74 | — | — | |
| SCHEMBL44272 | 0.73 | CA2 (0.38) | ALDH1A1CA2CHKACYP1A2MAPK1 | |
| SCHEMBL3795193 | 0.73 | CA2 (0.38) | ALDH1A1CA2CHKACYP1A2MAPK1 | |
| SCHEMBL29569270 | 0.72 | ALOX15 (0.35) | — | |
| SCHEMBL29569422 | 0.72 | ALOX15 (0.35) | — | |
| SCHEMBL3635059 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705649-A | Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents | ABBOTT LAB (US) | 2005-12-07 | — | — | CN | disclosed |