Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18432567 | 0.98 | — | — | |
| SCHEMBL2278325 | 0.91 | — | — | |
| SCHEMBL16104765 | 0.83 | — | — | |
| SCHEMBL15824158 | 0.81 | — | — | |
| SCHEMBL29569422 | 0.77 | ALOX15 (0.35) | — | |
| SCHEMBL3635059 | 0.77 | — | — | |
| SCHEMBL29569270 | 0.77 | ALOX15 (0.35) | — | |
| SCHEMBL27632519 | 0.77 | MAPT (0.50) | CA2CHKA | |
| SCHEMBL9449545 | 0.76 | CXCR4 (0.35) | — | |
| SCHEMBL18432572 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |
| EP-1336606-B1 | 6-Alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibers | OREAL (FR) | 2006-12-27 | — | — | EP | claimed |
| US-6916345-B2 | 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-07-12 | — | — | US | claimed |
| US-6837908-B2 | 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2005-01-04 | — | — | US | claimed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | claimed |
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2003-09-04 | — | — | US | claimed |
| EP-1336606-A1 | 6-Alkoxy-2,3-diaminopyridine couplers for dying keratin fibers | L'OREAL (FR) | 2003-08-20 | — | — | EP | claimed |
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | disclosed |
| US-7179307-B2 | Use of an extract of myrsine africana in oxidation dyeing for dyeing keratin fibres | L'OREAL, S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-20060010618-A1 | Use of an extract of Myrsine africana in oxidation dyeing for dyeing keratin fibres | L'OREAL S.A. | 2006-01-19 | — | — | US | disclosed |
| US-6974485-B2 | Use of an extract of Myrsine africana in oxidation dyeing for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-12-13 | — | — | US | disclosed |
| US-6916345-B2 | 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-07-12 | — | — | US | disclosed |
| EP-1312347-B1 | Use of an extract of myrsine africana for the oxidative dyeing of keratinic fibres | OREAL (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6837908-B2 | 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2005-01-04 | — | — | US | disclosed |
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-12-11 | — | — | US | disclosed |
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | L'OREAL S.A. (FR) | 2003-09-04 | — | — | US | disclosed |
| US-20030115687-A1 | Use of an extract of Myrsine africana in oxidation dyeing for dyeing keratin fibres | L'OREAL S.A. (FR) | 2003-06-26 | — | — | US | disclosed |
| EP-1312347-A1 | Use of an extract of myrsine africana for the oxidative dyeing of keratinic fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030226216-A1 | Novel 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres | KRT18, DSP, DPYD | MEN1 4578/4885CYP3A4 2741/4885CYP2C9 1878/4885 |
| US-20030163876-A1 | Novel 2,5-diaminopyridine oxidation bases for the dyeing of keratin fibres | KRT18, DPYD, DSP | MEN1 4750/4885CYP3A4 2704/4885CYP2C9 1692/4885 |
| US-20060010618-A1 | Use of an extract of Myrsine africana in oxidation dyeing for dyeing keratin fibres | KRT18, TUBB8, TUBB | MEN1 4344/4885CYP3A4 1630/4885CYP2C9 1739/4885 |
| US-20030115687-A1 | Use of an extract of Myrsine africana in oxidation dyeing for dyeing keratin fibres | KRT18, TUBB8, TUBB | MEN1 4344/4885CYP3A4 1630/4885CYP2C9 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.