Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405554 | 0.83 | LMNA (0.76) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL4669122 | 0.83 | LMNA (0.76) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL1889598 | 0.82 | KDM4E (0.59) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL7678596 | 0.82 | LMNA (0.88) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL4952951 | 0.81 | LMNA (0.63) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL845142 | 0.81 | LMNA (1.00) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL28842312 | 0.79 | LMNA (0.96) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL28842439 | 0.79 | LMNA (0.96) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL4955777 | 0.79 | PPARG (0.61) | LMNAHTTTP53NPC1GAA | |
| SCHEMBL4955789 | 0.77 | PPARG (0.73) | LMNAHTTTP53NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475776-C | Amino acid diamides in non alpha position useful as adjuvants for the administration of active biological agents | ROVI LAB FARMACEUT SA (ES) | 2009-04-08 | — | — | CN | disclosed |
| CN-1829682-A | Amino acid diamides in non-alpha positions useful as adjuvants for the administration of biologically active agents | ROVI LAB FARMACEUT SA (ES) | 2006-09-06 | — | — | CN | disclosed |