Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598345 | 0.89 | MEN1 (0.69) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL1548899 | 0.83 | MEN1 (0.74) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL29702370 | 0.83 | MEN1 (0.74) | KDM4EMEN1KMT2AMAPTRAB9A | |
| Salicylic Acid SCHEMBL844725 | 0.83 | ALDH1A1 (0.78) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL27633477 | 0.82 | LMNA (0.67) | KDM4EMEN1KMT2ARAB9AHPGD | |
| SCHEMBL31589529 | 0.81 | MEN1 (0.56) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL10788491 | 0.81 | KDM4E (0.59) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL2240149 | 0.81 | MEN1 (0.56) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL8028698 | 0.81 | CYP19A1 (0.58) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL31211720 | 0.79 | CYP19A1 (0.66) | KDM4EMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107176938-A | A kind of triketone organic compound and preparation method and application | 赵学辉 | 2017-09-19 | — | — | CN | claimed |
| CN-107176939-A | A kind of new tripodia ketone ligand organic compound and preparation method and application | 赵学辉 | 2017-09-19 | — | — | CN | claimed |
| JP-54141774-A | — | — | None | — | — | JP | disclosed |
| CN-107405337-A | Substituted chroman and application method | 艾伯维公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-107176938-A | A kind of triketone organic compound and preparation method and application | 赵学辉 | 2017-09-19 | — | — | CN | disclosed |
| CN-107176939-A | A kind of new tripodia ketone ligand organic compound and preparation method and application | 赵学辉 | 2017-09-19 | — | — | CN | disclosed |
| CN-107176939-A | A kind of new tripodia ketone ligand organic compound and preparation method and application | 赵学辉 | 2017-09-19 | — | — | CN | disclosed |
| CN-107176938-A | A kind of triketone organic compound and preparation method and application | 赵学辉 | 2017-09-19 | — | — | CN | disclosed |
| US-20110117649-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-05-19 | — | — | US | disclosed |
| US-7851640-B2 | Catalytic enantioselective synthesis of flavanones and chromanones | NORTHWESTERN UNIVERSITY (US) | 2010-12-14 | — | — | US | disclosed |
| US-20090259055-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-15 | — | — | US | disclosed |
| WO-2009108392-A2 | CATALYTIC ENANTIOSELECTIVE SYNTHESIS OF FLAVANONES AND CHROMANES | NORTHWESTERN UNIVERSITY (US) | 2009-09-03 | — | — | WO | disclosed |
| JP-S54141774-A | PREPARATION OF 4-HYDROXYCOUMARIN DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1979-11-05 | — | — | JP | disclosed |
| US-3931523-A | Activation neutron detector | AMBARDANISHVILI TRISTAN SILOVA | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259055-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | RNGTT, CDK20, TBXAS1 | KDM4E 1170/4885MEN1 4332/4885KMT2A 2596/4885 |
| US-20110117649-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | RNGTT, CDK20, TBXAS1 | KDM4E 1170/4885MEN1 4332/4885KMT2A 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.