Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009141 | 0.84 | ALDH1A1 (0.69) | ATMHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7278994 | 0.83 | SMN1; SMN2 (0.73) | ATMMAPTHTTLMNAFPR2 | |
| SCHEMBL15330611 | 0.79 | MAPT (0.64) | ATMMAPTHTTLMNAFPR2 | |
| SCHEMBL20964517 | 0.77 | MAPT (0.63) | ATMMAPTHTTLMNAFPR2 | |
| SCHEMBL7807313 | 0.77 | ATM (0.90) | ATMLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL17730978 | 0.76 | DRD2 (0.68) | ATMMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7544001 | 0.76 | HTT (0.80) | ATMMAPTHTTLMNAFPR2 | |
| Hydrochloric Acid SCHEMBL11669572 | 0.73 | ATM (0.52) | ATMMAPTHTTLMNAFPR2 | |
| SCHEMBL6893687 | 0.73 | ALDH1A1 (0.79) | ATMLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL23747357 | 0.73 | SMN1; SMN2 (0.63) | ATMHTTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1839131-A | Azolidinecarbonitriles and their use as DPP-IV inhibitors | TORRENT PHARMACEUTICALS LTD (IN) | 2006-09-27 | — | — | CN | disclosed |