Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.90 |
| ▸ | FAAH | O00519 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893687 | 0.85 | ALDH1A1 (0.79) | ATMMEN1KMT2AKCNA5ALDH1A1 | |
| SCHEMBL5749895 | 0.82 | ATM (0.78) | ATMFAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL8585760 | 0.81 | NPC1 (0.67) | ATMMEN1KMT2AKCNA5ALDH1A1 | |
| SCHEMBL24489123 | 0.81 | MEN1 (0.64) | ATMMEN1KMT2AKCNA5ALDH1A1 | |
| SCHEMBL29694124 | 0.81 | MEN1 (0.64) | ATMMEN1KMT2AKCNA5ALDH1A1 | |
| SCHEMBL14192211 | 0.81 | ALDH1A1 (0.72) | ATMMEN1KMT2AKCNA5ALDH1A1 | |
| SCHEMBL6093114 | 0.80 | FAAH (0.74) | ATMFAAHCA2SMN1; SMN2 | |
| SCHEMBL8585764 | 0.80 | REV1 (0.82) | ATMFAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL29057517 | 0.80 | ALDH1A1 (0.71) | ATMMEN1KMT2AALDH1A1CA1 | |
| SCHEMBL13595611 | 0.79 | ATM (0.69) | ATMMEN1KMT2AALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068193-A1 | BENZYLPIPERAZINYL- AND BENZYLPIPERIDINYL ETHANONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D 4? RECEPTOR ANTAGONISTS | NEUROGEN CORPORATION (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999043670-A1 | BENZYLPIPERAZINYL- AND BENZYLPIPERIDINYL ETHANONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D4 RECEPTOR ANTAGONISTS | NEUROGEN CORPORATION (US) | 1999-09-02 | — | — | WO | claimed |