Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | HMGCR | P04035 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254632 | 0.81 | SMN1; SMN2 (0.47) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL11263612 | 0.81 | IDO1 (0.53) | MAPTHSP90AB1CA9KDM4EALDH1A1 | |
| SCHEMBL23643783 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL27888697 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL4050618 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL30137706 | 0.78 | MEN1 (0.58) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL27451059 | 0.78 | GRIN2D (0.63) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL3893085 | 0.78 | MEN1 (0.58) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL11695943 | 0.78 | MEN1 (0.50) | MEN1KMT2AMAPTMITFGAA | |
| SCHEMBL2988486 | 0.77 | ALOX15 (0.69) | MEN1KMT2AMAPTTDP1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688549-A | Compound having TGF-beta inhibitory activity and medicinal composition containing the same | KIRIN BREWERY (JP) | 2005-10-26 | — | — | CN | disclosed |