SCHEMBL2988486

SCHEMBL2988486

CCC(=O)c1cc(O)c(O)cc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.69
ALDH1A1 P00352 3/20 0.69
HSD17B10 Q99714 3/20 0.69
HPGD P15428 2/20 0.69
TSHR P16473 1/20 0.69
RECQL P46063 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
HMGCR P04035 1/20 0.62
HSP90AB1 P08238 1/20 0.61
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
CA9 Q16790 2/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
PTGS1 P23219 1/20 0.50
DRD3 P35462 1/20 0.50
MAPT P10636 4/20 0.43
HTT P42858 4/20 0.43
LMNA P02545 3/20 0.43
MAPK1 P28482 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8895485 0.85 MAPT (0.60) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL22500207 0.83 HMGCR (0.55) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL12766931 0.83 HMGCR (0.55) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL15364117 0.83 HMGCR (0.55) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL29430367 0.82 ALOX15 (1.00) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL4841923 0.82 HMGCR (0.58) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL43001 0.82 ALOX15 (1.00) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL13284210 0.82 HSP90AB1 (0.52) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL24450831 0.80 HSP90AB1 (0.50) ALOX15ALDH1A1HSD17B10HPGDTSHR
SCHEMBL19425899 0.80 HSP90AB1 (0.50) ALOX15ALDH1A1HSD17B10HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
CN-110183431-A One kind is for liver disease or the compound of prevention 江苏新元素医药科技有限公司 2019-08-30 CN disclosed
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 US disclosed
US-7834210-B2 Hair loss prevention by natural amino acid and peptide complexes BIODERM RESEARCH (US) 2010-11-16 US disclosed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20090253668-A1 Hair Loss Prevention by Natural Amino Acid and Peptide Complexes BIODERM RESEARCH (US) 2009-10-08 US disclosed
US-7572933-B2 Skin and hair restoration by natural amino acid peptide complexes BIODERM RESEARCH (US) 2009-08-11 US disclosed
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents BIODERM RESEARCH (US) 2009-03-19 US disclosed
US-20080287536-A1 Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes BIODERM RESEARCH (US) 2008-11-20 US disclosed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US disclosed
US-20080139507-A1 Method of Treating Skin Condition Including Acne, Skin Aging, Body Odor & Diaper Rash by Zinc Zeolite Clathrates BIODERM RESEARCH (US) 2008-06-12 US disclosed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 ALOX15 8/4885ALDH1A1 110/4885HSD17B10 210/4885
US-20090074691-A1 Topical Delivery System for Antiaging and Skin Whitening Agents TYR, MMP17, MMP1 ALOX15 14/4885ALDH1A1 567/4885HSD17B10 44/4885
US-20080287536-A1 Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes MMP17, MC1R, TYR ALOX15 502/4885ALDH1A1 3352/4885HSD17B10 711/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA ALOX15 266/4885ALDH1A1 330/4885HSD17B10 806/4885
US-20090253668-A1 Hair Loss Prevention by Natural Amino Acid and Peptide Complexes MMP1, MMP17, MMP13 ALOX15 768/4885ALDH1A1 1360/4885HSD17B10 160/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA ALOX15 184/4885ALDH1A1 35/4885HSD17B10 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.