SCHEMBL3893085

SCHEMBL3893085

CC(=O)c1cc2ccccc2cc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
MAPT P10636 5/20 0.58
MITF O75030 1/20 0.58
GAA P10253 1/20 0.58
NCOA1 Q15788 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
NCOA3 Q9Y6Q9 1/20 0.58
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
POLB P06746 5/20 0.57
CASP3 P42574 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
KDM4E B2RXH2 4/20 0.51
CA9 Q16790 2/20 0.51
MAOB P27338 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MAOA P21397 1/20 0.51
CASP1 P29466 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30137706 1.00 MEN1 (0.58) MEN1KMT2AMAPTMITFGAA
SCHEMBL28466533 0.86 KDM4E (0.57) MEN1KMT2AMAPTMITFGAA
SCHEMBL1667141 0.82 KDM4E (0.53) MEN1KMT2AMAPTMITFGAA
SCHEMBL16355668 0.80 CYP2A6 (0.55) MEN1KMT2ATDP1NPC1RAB9A
Acetamide SCHEMBL10951863 0.80 IDO1 (0.56) MEN1KMT2AMAPTMITFGAA
SCHEMBL6460 0.80 GRIN2D (0.66) MEN1KMT2AMAPTMITFGAA
SCHEMBL27593821 0.80 MEN1 (0.60) MEN1KMT2AMAPTMITFGAA
SCHEMBL29358330 0.80 GRIN2D (0.66) MEN1KMT2AMAPTMITFGAA
SCHEMBL6697937 0.78 GRIN2D (0.63) MEN1KMT2AMAPTMITFGAA
SCHEMBL11268428 0.78 IDO1 (0.59) MAPTPOLBKDM4ECA9MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365851-A1 THERMALLY CONDUCTIVE ADDITIVE, THERMALLY CONDUCTIVE COMPOSITE MATERIAL, AND WIRE HARNESS AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2023-11-16 US disclosed
US-20230365851-A1 THERMALLY CONDUCTIVE ADDITIVE, THERMALLY CONDUCTIVE COMPOSITE MATERIAL, AND WIRE HARNESS AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2023-11-16 US disclosed
CN-115475249-A Photoresponse carbon monoxide release nanogel and preparation method and application thereof 西北工业大学 2022-12-16 CN disclosed
US-20220119376-A1 TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2022-04-21 US disclosed
EP-3848367-A1 TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2021-07-14 EP disclosed
WO-2020132603-A2 SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2020-06-25 WO disclosed
US-9840488-B2 Carbon monoxide releasing molecules and associated methods UTAH STATE UNIVERSITY (US) 2017-12-12 US disclosed
US-9840488-B2 Carbon monoxide releasing molecules and associated methods UTAH STATE UNIVERSITY (US) 2017-12-12 US disclosed
US-9840488-B2 Carbon monoxide releasing molecules and associated methods UTAH STATE UNIVERSITY (US) 2017-12-12 US disclosed
EP-2290015-B1 NANOSCALE PIGMENT PARTICLE COMPOSITION AND PROCESS FOR PRODUCING THE SAME XEROX CORP (US) 2017-05-24 EP disclosed
US-20060111375-A1 Compound having tgfß inhibitory activity and medicinal composition containing the same KIRIN BEER KABUSHIKI KAISHA (JP) 2006-05-25 US disclosed
EP-1548008-A1 COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND MEDICINAL COMPOSITION CONTAINING THE SAME KIRIN BEER KABUSHIKI KAISHA (JP) 2005-06-29 EP disclosed
US-5855661-A METALLO, MONO AND BI-DENTATE LIGAND PIGMENT PARTICLES WITH A SURFACE DERIVATIZING AGENT HAVING ONE OR MORE PHENOLIC MOIETIES, A 1, 3-DIKETO MOIETY OR A COMBINATION THEREOF. VIDEOJET SYSTEMS INTERNATIONAL, INC. (US) 1999-01-05 US disclosed
US-5849074-A Method for preparing magnetic ink and dry pigment particles used therefor VIDEOJET SYSTEMS INTERNATIONAL, INC. (US) 1998-12-15 US disclosed
EP-0876432-A1 METHOD FOR PREPARING MODIFIED MAGNETIC PIGMENT PARTICLES VIDEOJET SYSTEMS INTERNATIONAL, INC. (US) 1998-11-11 EP disclosed
US-5645768-A PYRAN IN WHICH AROMATIC RESIDUES ARE RIGIDLY ATTACHED TO A SPIROPYRAN; TINTING OPTICAL PLASTIC MATERIAL OPTISCHE WERKE G. RODENSTOCK (DE) 1997-07-08 US disclosed
WO-1997012941-A1 METHOD FOR PREPARING MODIFIED MAGNETIC PIGMENT PARTICLES VIDEOJET SYSTEMS INTERNATIONAL, INC. (US) 1997-04-10 WO disclosed
EP-0010842-B1 POLYURETHANE FOAM AND METHOD OF PREPARATION THEREOF UNIROYAL LTD. (CA) 1983-09-21 EP disclosed
US-4209593-A Semi-flexible shock-absorbing polyurethane foam prepared from a triol, a compound having a single reactive hydrogen, an aromatic polyisocyanate, blowing agent, chain-extender and a catalyst UNIROYAL LTD. (CA) 1980-06-24 US disclosed
EP-0010842-A1 Polyurethane foam and method of preparation thereof UNIROYAL LTD. (CA) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220119376-A1 TRICYCLIC COMPOUNDS ACTING ON CRBN PROTEINS CRBN, CSNK2A1, CSNK2A2 MEN1 3379/4885KMT2A 2165/4885MAPT 539/4885
US-20060111375-A1 Compound having tgfß inhibitory activity and medicinal composition containing the same TGFB1, TGFBR1, TGFBR2 MEN1 1660/4885KMT2A 2521/4885MAPT 2587/4885
US-20230365851-A1 THERMALLY CONDUCTIVE ADDITIVE, THERMALLY CONDUCTIVE COMPOSITE MATERIAL, AND WIRE HARNESS ILK, TPR, PIEZO1 MEN1 871/4885KMT2A 2539/4885MAPT 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.