Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.63 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635469 | 0.86 | BCAT2 (0.62) | BCAT2SCN9ACHEK1ALOX5APFEN1 | |
| SCHEMBL31583298 | 0.84 | BCAT2 (0.51) | BCAT2SCN9ACHEK1ALOX5APFEN1 | |
| SCHEMBL6187171 | 0.83 | BCAT2 (0.50) | BCAT2SCN9ACHEK1ALOX5APFEN1 | |
| SCHEMBL27656527 | 0.82 | AR (0.51) | BCAT2SCN9ACHEK1ALOX5APFEN1 | |
| Trifluoroacetic Acid SCHEMBL31255509 | 0.80 | BCAT2 (0.79) | BCAT2CHEK1ALOX5APFEN1PDK2 | |
| Trifluoroacetic Acid SCHEMBL1786045 | 0.80 | BCAT2 (0.79) | BCAT2CHEK1ALOX5APFEN1PDK2 | |
| SCHEMBL5494348 | 0.80 | MAPK8 (0.51) | BCAT2CHEK1S1PR1PDK2RORB | |
| SCHEMBL27656528 | 0.80 | BCAT2 (0.54) | BCAT2SCN9ACHEK1S1PR1PDK2 | |
| SCHEMBL31140008 | 0.79 | BCAT2 (0.92) | BCAT2CHEK1IKBKBKDM4EALDH1A1 | |
| SCHEMBL132986 | 0.79 | BCAT2 (1.00) | BCAT2CHEK1IKBKBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102793692-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP | 2012-11-28 | — | — | CN | claimed |
| CN-1826120-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2006-08-30 | — | — | CN | claimed |