Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | RORB | Q92753 | 2/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31583298 | 0.84 | BCAT2 (0.51) | BCAT2RORBCHEK1ALOX5APFEN1 | |
| SCHEMBL27635470 | 0.83 | BCAT2 (0.63) | BCAT2RORBCHEK1ALOX5APFEN1 | |
| SCHEMBL27635469 | 0.80 | BCAT2 (0.62) | BCAT2CHEK1ALOX5APFEN1LMNA | |
| SCHEMBL5494348 | 0.80 | MAPK8 (0.51) | BCAT2RORBCHEK1LMNAPDK2 | |
| SCHEMBL28260267 | 0.79 | BCAT2 (0.45) | BCAT2CHEK1ALOX5APFEN1LMNA | |
| SCHEMBL7808032 | 0.78 | AR (0.58) | ALOX5APFEN1LMNAMAPTMEN1 | |
| SCHEMBL6187361 | 0.78 | BCAT2 (0.44) | BCAT2CHEK1ALOX5APFEN1SCN9A | |
| SCHEMBL27656527 | 0.77 | AR (0.51) | BCAT2RORBCHEK1ALOX5APFEN1 | |
| SCHEMBL2564888 | 0.75 | BCAT2 (0.65) | BCAT2PARP1SMN1; SMN2GAA | |
| SCHEMBL31315851 | 0.75 | NOTUM (0.45) | RORBTAS2R14ALOX5APFEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572686-A1 | ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | Novartis AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052884-A1 | ANTHRANILIC ACID AMIDE DERIVATIVES AND THEIR PHARMACEUTICAL USE | NOVARTIS AG (CH) | 2004-06-24 | — | — | WO | disclosed |