Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 12/20 | 0.81 |
| ▸ | LPAR1 | Q92633 | 11/20 | 0.81 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.59 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.57 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.49 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.49 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL27549117 | 0.99 | LPAR3 (0.84) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| Monoethanolamine SCHEMBL27411197 | 0.99 | LPAR3 (0.84) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| Monoethanolamine SCHEMBL29057722 | 0.92 | LPAR3 (0.72) | LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL2732573 | 0.91 | LPAR3 (0.97) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| SCHEMBL370759 | 0.91 | LPAR3 (0.97) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| Monoethanolamine SCHEMBL27966570 | 0.91 | LPAR3 (0.70) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| Monoethanolamine SCHEMBL27966440 | 0.91 | LPAR3 (0.70) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| Monoethanolamine SCHEMBL27966443 | 0.91 | LPAR3 (0.70) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| Alcohol SCHEMBL27915917 | 0.90 | LPAR3 (0.94) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| SCHEMBL10896195 | 0.90 | LPAR3 (1.00) | LPAR3LPAR1LPAR2LPAR5PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221556-A | Ionizable cationic lipid material, and preparation method and application thereof | 南京吉迈生物技术有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-103228284-A | Methods and compositions for preventing conditions | CYVAX INC | 2013-07-31 | — | — | CN | disclosed |
| CN-101237854-B | Lipid construct for delivery of insulin to a mammal | SDG INC | 2013-03-27 | — | — | CN | disclosed |
| CN-101014323-B | Phospholipid gel compositions for drug delivery and methods of treating conditions using same | IDEXX LAB INC | 2012-09-05 | — | — | CN | disclosed |
| CN-101969987-A | Long interspersed nuclear element polypeptide compositions and methods of use thereof | DAVID GLADSTONE INST | 2011-02-09 | — | — | CN | disclosed |
| CN-101557823-A | Human endogenous retroviral polypeptide compositions and methods of use thereof | UNIV CALIFORNIA (US) | 2009-10-14 | — | — | CN | disclosed |
| CN-101014323-A | Phospholipid gel compositions for drug delivery and methods of treating conditions using same | IDEXX LAB INC (US) | 2007-08-08 | — | — | CN | disclosed |
| CN-1838964-A | Treatment and prevention of pulmonary diseases | SCRIPPS RESEARCH INST (US) | 2006-09-27 | — | — | CN | disclosed |