SCHEMBL28579337

SCHEMBL28579337

CCCCCNC=Cc1ccc(CC)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
PTGS1 P23219 1/20 0.40
PTGS2 P35354 1/20 0.40
HRH4 Q9H3N8 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
EPHX1 P07099 1/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
TUBB1 Q9H4B7 1/20 0.38
EGFR P00533 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TNNC1 P63316 1/20 0.37
SPHK2 Q9NRA0 1/20 0.37
SPHK1 Q9NYA1 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321625 0.83 ESR1 (0.44) PTGS1PTGS2EGFRMAOBLMNA
SCHEMBL1506756 0.82 EGFR (0.54) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL10628483 0.81 EGFR (0.56) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL27636014 0.81 EGFR (0.56) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL10623848 0.81 EGFR (0.56) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL27881206 0.80 ALDH1A1 (0.49) ALOX5PTGS1PTGS2TUBB1CYP1A2
SCHEMBL10628647 0.77 HDAC3 (0.51) ADH1BADH1CADH1AADH7TUBB1
SCHEMBL28375109 0.76 CA2 (0.45) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL23181695 0.74 ALOX5 (0.47) ALOX5PTGS1PTGS2TUBB1SMN1; SMN2
SCHEMBL6546261 0.72 ALOX5 (0.63) ALOX5PTGS1PTGS2TUBB1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108623425-B Method for constructing four-membered ring by visible light catalysis [2+2] reaction 中国科学院理化技术研究所 2021-05-14 CN disclosed