Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.56 |
| ▸ | F10 | P00742 | 5/20 | 0.55 |
| ▸ | CCR2 | P41597 | 4/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636281 | 0.87 | CCR2 (0.54) | PLA2G10F10CCR2NOD2NOD1 | |
| SCHEMBL13127957 | 0.81 | CCR2 (0.59) | PLA2G10F10CCR2NOD2NOD1 | |
| SCHEMBL25145010 | 0.77 | CCR2 (0.67) | PLA2G10F10CCR2NOD2NOD1 | |
| SCHEMBL1573798 | 0.76 | PLA2G10 (0.78) | PLA2G10F10CCR2NOD2NOD1 | |
| SCHEMBL30044340 | 0.76 | CCR2 (0.58) | PLA2G10F10CCR2NOD2NOD1 | |
| SCHEMBL13738783 | 0.76 | CCR2 (0.58) | PLA2G10F10CCR2NOD2NOD1 | |
| SCHEMBL7087440 | 0.76 | KDM4E (0.55) | PLA2G10F10CCR2KMT2AALDH1A1 | |
| SCHEMBL20609049 | 0.76 | HDAC3 (0.53) | PLA2G10F10CCR2MCL1ALDH1A1 | |
| SCHEMBL30622530 | 0.76 | HDAC3 (0.53) | PLA2G10F10CCR2MCL1ALDH1A1 | |
| SCHEMBL27597968 | 0.75 | CCR2 (0.62) | CCR2KMT2AMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1723020-A | Indole derivatives as beta-2 agonists | PFIZER LTD (US) | 2006-01-18 | — | — | CN | disclosed |