SCHEMBL27636745

SCHEMBL27636745

N#Cc1ccc(Oc2ccc([N+](=O)[O-])c(O)c2)cc1C#N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
HPGD P15428 3/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GPR35 Q9HC97 1/20 0.45
VCAM1 P19320 1/20 0.44
CYP19A1 P11511 1/20 0.43
PDE4B Q07343 1/20 0.41
CTSB P07858 2/20 0.41
EGFR P00533 2/20 0.40
MERTK Q12866 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27657684 0.89 EGFR (0.46) ALDH1A1HPGDMAPTKDM4ELMNA
Hydroquinone SCHEMBL11475895 0.85 EGFR (0.44) ALDH1A1HPGDMAPTKDM4ELMNA
SCHEMBL4847049 0.83 GPR35 (0.58) ALDH1A1HPGDMAPTKDM4ELMNA
SCHEMBL11475898 0.82 MERTK (0.48) ALDH1A1HPGDMAPTKDM4ECYP1A2
SCHEMBL11481976 0.80 VCAM1 (0.62) ALDH1A1HPGDMAPTCYP1A2POLB
SCHEMBL4839671 0.80 GPR35 (0.55) ALDH1A1HPGDMAPTKDM4ELMNA
SCHEMBL27657688 0.79 F10 (0.42) ALDH1A1HPGDMAPTKDM4ELMNA
SCHEMBL16628146 0.79 HSPB1 (0.53) ALDH1A1HPGDMAPTKDM4ELMNA
SCHEMBL4840927 0.79 GPR35 (0.53) ALDH1A1HPGDMAPTKDM4ELMNA
SCHEMBL1980405 0.78 MEN1 (0.52) ALDH1A1MAPTKDM4EPOLBVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100443464-C AB type dibasic aminoacid monomer containing hydroxy group and its preparation method UNIV SICHUAN (CN) 2008-12-17 CN disclosed
CN-1865225-A AB type dibasic aminoacid monomer containing hydroxy group and its preparation method UNIV SICHUAN (CN) 2006-11-22 CN disclosed