Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583285 | 0.92 | GPR35 (0.51) | GPR35KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL4847049 | 0.91 | GPR35 (0.58) | GPR35KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL4839671 | 0.88 | GPR35 (0.55) | GPR35KDM4EALDH1A1CTSBMAPT | |
| SCHEMBL4843320 | 0.85 | GPR35 (0.51) | GPR35KDM4EALDH1A1CRHBPCRHR2 | |
| SCHEMBL4847624 | 0.85 | GPR35 (0.51) | GPR35KDM4EALDH1A1CTSBMAPT | |
| SCHEMBL4845235 | 0.84 | GPR35 (0.47) | GPR35KDM4EALDH1A1F10CTSB | |
| SCHEMBL11777721 | 0.84 | ALDH1A1 (0.57) | GPR35KDM4EALDH1A1F10MAPT | |
| SCHEMBL5955410 | 0.83 | LTA4H (0.52) | GPR35ALDH1A1MAPTLMNAHTT | |
| SCHEMBL27834942 | 0.83 | POLB (0.50) | KDM4EALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL4845296 | 0.82 | GPR35 (0.49) | GPR35KDM4EALDH1A1F10CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365231-B2 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE & TECHNOLOGY (TW) | 2008-04-29 | — | — | US | disclosed |
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241187-A1 | Compound with antitumor activity and preparation method therefor | WEE1, WEE2, CYP51A1 | GPR35 2929/4885KDM4E 2008/4885ALDH1A1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.