Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | WNT3 | P56703 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069075 | 0.89 | MAPT (0.47) | TSHRALOX15HSD17B10NPC1ALDH1A1 | |
| SCHEMBL27637282 | 0.89 | RAB9A (0.48) | TSHRTHRBALDH1A1NAMPTRAB9A | |
| SCHEMBL6011774 | 0.88 | ALDH1A1 (0.53) | TSHRALOX15HSD17B10NPC1ALDH1A1 | |
| SCHEMBL27637229 | 0.88 | GAA (0.45) | NPC1ALDH1A1MAPTWNT3SFRP1 | |
| SCHEMBL27637238 | 0.86 | WNT3 (0.40) | NPC1ALDH1A1WNT3SFRP1 | |
| SCHEMBL10069713 | 0.84 | ALDH1A1 (0.49) | TSHRALOX15HSD17B10NPC1ALDH1A1 | |
| SCHEMBL6011051 | 0.84 | ALOX15 (0.48) | TSHRALOX15HSD17B10NPC1ALDH1A1 | |
| SCHEMBL10069198 | 0.83 | TSHR (0.50) | TSHRALOX15HSD17B10NPC1ALDH1A1 | |
| SCHEMBL14261817 | 0.83 | TSHR (0.50) | TSHRALOX15HSD17B10NPC1ALDH1A1 | |
| SCHEMBL6011036 | 0.83 | ALOX15 (0.50) | TSHRALOX15HSD17B10NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1756740-A | Nitrogen-containing heterocyclic derivatives having 2, 6-disubstituted styryl group | ASTELLAS PHARMA INC (JP) | 2006-04-05 | — | — | CN | claimed |
| CN-1756740-A | Nitrogen-containing heterocyclic derivatives having 2, 6-disubstituted styryl group | ASTELLAS PHARMA INC (JP) | 2006-04-05 | — | — | CN | disclosed |