Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763241 | 0.89 | SMN1; SMN2 (0.51) | MEN1KMT2AHRH3EPHX2 | |
| SCHEMBL2763577 | 0.85 | OPRK1 (0.56) | HRH3EPHX2HTR2AHTR7 | |
| SCHEMBL24596936 | 0.83 | HRH3 (0.54) | MEN1KMT2AHRH3EPHX2HTR2A | |
| SCHEMBL30775358 | 0.83 | EPHX2 (0.46) | HRH3EPHX2 | |
| SCHEMBL2763728 | 0.82 | MMP13 (0.50) | MEN1KMT2AHRH3EPHX2 | |
| SCHEMBL14924453 | 0.79 | HRH3 (0.69) | MEN1KMT2AHRH3HTR2AHTR7 | |
| SCHEMBL6263206 | 0.78 | ALDH1A1 (0.57) | HRH3EPHX2 | |
| SCHEMBL30775212 | 0.78 | ADRB2 (0.50) | — | |
| SCHEMBL15829867 | 0.78 | HRH3 (0.52) | MEN1KMT2AHRH3EPHX2HTR2A | |
| SCHEMBL15652082 | 0.77 | HRH3 (0.46) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592595-B2 | Preparation of (N-heterocyclyl) aryl ethers | SALTIGO GMBH (DE) | 2013-11-26 | — | — | US | claimed |
| US-20100152454-A1 | PREPARATION OF (N-HETEROCYCLYL) ARYL ETHERS | SALTIGO GMBH (DE) | 2010-06-17 | — | — | US | claimed |
| EP-2179988-A1 | Producing (N-heterocyclic) aryl ethers | Saltigo GmbH (DE) | 2010-04-28 | — | — | EP | claimed |
| US-8592595-B2 | Preparation of (N-heterocyclyl) aryl ethers | SALTIGO GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| US-20100152454-A1 | PREPARATION OF (N-HETEROCYCLYL) ARYL ETHERS | SALTIGO GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| EP-2179988-A1 | Producing (N-heterocyclic) aryl ethers | Saltigo GmbH (DE) | 2010-04-28 | — | — | EP | disclosed |