Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314345 | 0.84 | TSHR (0.48) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL2726052 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL11147325 | 0.81 | MAPT (0.53) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL9370719 | 0.81 | TSHR (0.53) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL1733955 | 0.81 | MGLL (0.57) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL28032033 | 0.80 | ACHE (0.44) | ALDH1A1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL5693941 | 0.79 | LMNA (0.54) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL10879659 | 0.79 | LMNA (0.58) | ALDH1A1MAPTGAAHPGDHTT | |
| SCHEMBL27886152 | 0.79 | F2 (0.52) | ALDH1A1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL27470803 | 0.78 | ACHE (0.43) | ALDH1A1MAPTGAAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100448867-C | 1,2,4-triaminobenzenderivater nyttige for behandling AV forstyrrelser i sentralnervesystemet | LUNDBECK & CO AS H (DK) | 2009-01-07 | — | — | CN | disclosed |
| CN-1732162-A | 1,2,4-triaminobenzenderivater nyttige for behandling AV forstyrrelser i sentralnervesystemet | LUNDBECK & CO AS H (DK) | 2006-02-08 | — | — | CN | disclosed |