Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775014 | 0.84 | ALDH1A1 (0.51) | COMTALDH1A1MAPTKMT2AMAPK1 | |
| SCHEMBL27897186 | 0.83 | MAPK1 (0.53) | COMTALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL1185712 | 0.78 | MAPT (0.49) | ALDH1A1MAPTGAAKMT2AMAPK1 | |
| SCHEMBL2203444 | 0.76 | PARP1 (0.59) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL309017 | 0.76 | PARP1 (0.59) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL27697310 | 0.75 | HCAR3 (0.55) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL11705097 | 0.73 | GPR35 (0.51) | COMTALDH1A1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL5526148 | 0.73 | GSK3B (0.57) | COMTALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL16914851 | 0.70 | MAPK1 (0.51) | COMTALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7047805 | 0.70 | TSHR (0.68) | ALDH1A1MAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882602-A | Modulation and degradation of hyaluronan synthesis in the treatment of disease | MEDITECH RES LTD (AU) | 2006-12-20 | — | — | CN | claimed |
| CN-1761517-A | Mixing device | HENKEL KGAA (DE) | 2006-04-19 | — | — | CN | disclosed |