Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767494 | 0.77 | SIGMAR1 (0.56) | MAPTNPSR1HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27456703 | 0.77 | CYP1A2 (0.51) | MAPTALDH1A1MEN1KMT2AHTR6 | |
| SCHEMBL27638449 | 0.76 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL2767154 | 0.75 | ADRB1 (0.56) | MAPTALDH1A1SMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL27659294 | 0.75 | HSP90AA1 (0.44) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16742541 | 0.75 | INSR (0.46) | MAPTALDH1A1SMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL2767279 | 0.75 | POLB (0.53) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL28757770 | 0.68 | ME2 (0.42) | MAPTALDH1A1SMN1; SMN2ALOX15RAB9A | |
| SCHEMBL17050468 | 0.66 | MRGPRX4 (0.58) | MAPTALDH1A1SMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL27638459 | 0.66 | ME2 (0.62) | MAPTALDH1A1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100467449-C | Cyclic aminophenyl sulfamate derivative | ASKA PHARM CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-1823039-A | Cyclic aminophenyl sulfamate derivative | ASKA PHARM CO LTD (JP) | 2006-08-23 | — | — | CN | disclosed |