Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020241 | 0.91 | BACE1 (0.51) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL8010389 | 0.90 | BACE1 (0.53) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL12702799 | 0.88 | TRPV1 (0.46) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL8021150 | 0.87 | ICMT (0.45) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL27639564 | 0.84 | PPARG (0.45) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL27660340 | 0.83 | PTGES (0.46) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL12702765 | 0.82 | PPARG (0.47) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL8011289 | 0.81 | PPARG (0.46) | PPARGPPARDPPARADNMT1SIRT5 | |
| SCHEMBL9417828 | 0.79 | NPC1 (0.49) | NPC1HPGDRAB9ASMN1; SMN2EGFR | |
| SCHEMBL8026218 | 0.79 | ALDH1A1 (0.43) | PPARGPPARDPPARADNMT1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | claimed |
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | disclosed |