Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956817 | 0.72 | NCF1 (0.39) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6923638 | 0.71 | POLB (0.47) | CYP11B1CYP11B2RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL29447706 | 0.70 | CYP11B1 (0.35) | CYP11B1CYP11B2NPC1RAB9AHPGD | |
| SCHEMBL28067981 | 0.70 | MAPT (0.32) | — | |
| SCHEMBL20401326 | 0.69 | ACSS2 (0.39) | NPC1RAB9AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL18113496 | 0.69 | RECQL (0.44) | CYP11B1CYP11B2RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL30554368 | 0.69 | RECQL (0.44) | CYP11B1CYP11B2RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14895594 | 0.68 | PDPK1 (0.43) | — | |
| SCHEMBL12042936 | 0.68 | CYP11B1 (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL21996476 | 0.67 | ALDH1A1 (0.34) | CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100343260-C | Cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 2007-10-17 | — | — | CN | disclosed |
| CN-1708502-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-12-14 | — | — | CN | disclosed |