Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | QDPR | P09417 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5661763 | 0.86 | DRD2 (0.50) | DRD2ADRA1AQDPRTLR9TLR8 | |
| SCHEMBL4775482 | 0.81 | WDR5 (0.41) | TLR9TLR8TLR7 | |
| SCHEMBL27640757 | 0.80 | MAPK14 (0.42) | QDPRMAPK14TLR9TLR8TLR7 | |
| SCHEMBL5342788 | 0.79 | DRD2 (0.38) | DRD2ADRA1ATLR9TLR8TLR7 | |
| SCHEMBL4764984 | 0.78 | NAMPT (0.56) | JAK3NAMPT | |
| SCHEMBL4768317 | 0.77 | DRD2 (0.54) | DRD2ADRA1A | |
| SCHEMBL5345157 | 0.77 | DRD2 (0.47) | DRD2ADRA1A | |
| SCHEMBL4791557 | 0.76 | DRD2 (0.54) | DRD2ADRA1AHTR2C | |
| SCHEMBL27649135 | 0.73 | PKM (0.47) | NAMPT | |
| SCHEMBL29177436 | 0.73 | GLA (0.46) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735595-A | Substituted alkyl amido piperidines | LUNDBECK & CO AS H (DK) | 2006-02-15 | — | — | CN | disclosed |