Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649135 | 0.83 | PKM (0.47) | GAARAB9A | |
| SCHEMBL3986564 | 0.81 | HDAC1 (0.49) | POLBGAARAB9A | |
| SCHEMBL27640735 | 0.80 | DRD2 (0.47) | MAPK14QDPRTLR9TLR8TLR7 | |
| SCHEMBL6365423 | 0.80 | KMT2A (0.47) | GAARAB9A | |
| SCHEMBL4776810 | 0.79 | TP53 (0.55) | RAB9A | |
| SCHEMBL4769696 | 0.79 | CYP3A4 (0.50) | — | |
| SCHEMBL27621992 | 0.78 | NMT2 (0.50) | RAB9ANMT2NMT1 | |
| SCHEMBL3811973 | 0.78 | HDAC2 (0.46) | MAPK14RAB9A | |
| SCHEMBL6365745 | 0.78 | HDAC1 (0.50) | POLB | |
| SCHEMBL3992483 | 0.78 | DRD2 (0.49) | MAPK14RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1735595-A | Substituted alkyl amido piperidines | LUNDBECK & CO AS H (DK) | 2006-02-15 | — | — | CN | disclosed |