SCHEMBL27640980

SCHEMBL27640980

Oc1ccc(S)c(-c2ccc(F)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.45
HPGD P15428 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
GLA P06280 1/20 0.45
POLB P06746 1/20 0.45
MIF P14174 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSD17B10 Q99714 2/20 0.44
NPC1 O15118 2/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ESR2 Q92731 5/20 0.42
ESR1 P03372 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674576 0.79 ALOX5 (0.59) RAB9AKDM4EALDH1A1HPGDMEN1
SCHEMBL9009159 0.79 KDM4E (0.47) RAB9AKDM4EALDH1A1GAAHPGD
SCHEMBL2861901 0.79 ALOX5 (0.59) RAB9AKDM4EALDH1A1HPGDMEN1
SCHEMBL6068025 0.77 ALOX5 (0.61) RAB9AKDM4EALDH1A1GAAHPGD
SCHEMBL28902201 0.76 ALOX5 (0.54) MIFESR2ESR1HSD17B1HSD17B2
SCHEMBL321906 0.76 HSD17B10 (0.46) RAB9AKDM4EALDH1A1GAAHPGD
SCHEMBL9842662 0.75 ESR1 (0.66) RAB9AKDM4EALDH1A1GAAHPGD
SCHEMBL27870662 0.73 HSD17B1 (0.55) RAB9AKDM4EALDH1A1GAAHPGD
SCHEMBL23319252 0.72 ESR2 (0.66) RAB9AKDM4EALDH1A1GAAHPGD
SCHEMBL322288 0.72 ESR1 (0.61) RAB9AKDM4EALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1853141-A Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2006-10-25 CN disclosed