SCHEMBL2861901

SCHEMBL2861901

Oc1ccc(S)c(-c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
ESR2 Q92731 5/20 0.53
BACE1 P56817 2/20 0.50
PELI1 Q96FA3 1/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
MPI P34949 1/20 0.47
KMT2A Q03164 1/20 0.47
BCL2L1 Q07817 2/20 0.46
MMP3 P08254 1/20 0.46
ESR1 P03372 4/20 0.45
HSD17B10 Q99714 1/20 0.43
NPC1 O15118 2/20 0.42
MIF P14174 1/20 0.42
HSP90AA1 P07900 1/20 0.42
CA12 O43570 1/20 0.42
ALDH2 P05091 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674576 1.00 ALOX5 (0.59) ALOX5ESR2BACE1PELI1ALDH1A1
SCHEMBL3802935 0.79 ALOX5 (0.74) ALOX5ESR2BACE1PELI1ALDH1A1
SCHEMBL503746 0.79 ALOX5 (0.74) ALOX5ESR2BACE1PELI1ALDH1A1
SCHEMBL27640980 0.79 RAB9A (0.45) ALOX5ESR2PELI1ALDH1A1HPGD
SCHEMBL28978920 0.79 ACHE (0.50) ALOX5ESR2PELI1ESR1CA12
SCHEMBL28937432 0.78 MAPK1 (0.46) ALOX5BACE1ALDH1A1HPGDKDM4E
SCHEMBL17779550 0.78 BACE1 (0.56) ALOX5ESR2BACE1PELI1ALDH1A1
SCHEMBL68984 0.77 ALOX5 (0.71) ALOX5ESR2BACE1PELI1ALDH1A1
SCHEMBL31121009 0.77 ALOX5 (0.71) ALOX5ESR2BACE1PELI1ALDH1A1
SCHEMBL29458798 0.77 ALOX5 (0.71) ALOX5ESR2BACE1PELI1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047807-A C1 symmetrical chiral diphosphine ligand, and preparation method and application thereof 百色学院 2024-05-17 CN claimed
CN-111632594-B Method for regulating and controlling surface plasmon photocatalysis and application 南京工业大学 2022-12-09 CN claimed
CN-111944092-B Modified butadiene rubber and composite material and preparation method thereof 宁波大学 2022-06-17 CN claimed
CN-114573486-A Simple method for enhancing plasmon-driven photochemical decarboxylation reaction 南京工业大学 2022-06-03 CN claimed
CN-113666854-B Preparation method of symmetrical disulfide bond-containing compound 南京工业大学 2022-04-12 CN claimed
CN-113666854-A Preparation method of symmetrical disulfide bond-containing compound 南京工业大学 2021-11-19 CN claimed
CN-112225255-B Noble metal-loaded ordered double-mesoporous metal oxide composite material and preparation method thereof 复旦大学 2021-10-26 CN claimed
CN-112898899-A ZnO nanoflower grafted polymethyl methacrylate composite coating and preparation method thereof 杭州伍元新型材料有限公司 2021-06-04 CN claimed
CN-112225255-A Noble metal-loaded ordered double-mesoporous metal oxide composite material and preparation method thereof 复旦大学 2021-01-15 CN claimed
CN-111944092-A Modified butadiene rubber and composite material and preparation method thereof 宁波大学 2020-11-17 CN claimed
CN-111632594-A Method for regulating and controlling surface plasmon photocatalysis and application 南京工业大学 2020-09-08 CN claimed
CN-111112596-A Chiral noble metal nano-particles and preparation method and application thereof 国家纳米科学中心 2020-05-08 CN claimed
CN-110893334-A Polyphosphazene fluorescence-surface enhanced Raman coding microsphere and preparation method thereof 福州大学 2020-03-20 CN claimed
CN-110804743-A Dehydroxyreduction method of p-hydroxyphenylthiophenol 李旭 2020-02-18 CN claimed
CN-110684017-A High-stability near-infrared two-region small-molecule fluorescent probe and preparation method and application thereof 苏州大学 2020-01-14 CN claimed
CN-118047807-A C1 symmetrical chiral diphosphine ligand, and preparation method and application thereof 百色学院 2024-05-17 CN disclosed
CN-114815428-B Photochromic materials 惠州市华阳光学技术有限公司 2024-04-26 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed
US-3947468-A Production of dibenzopyrans, their isomeric fluorenols and dibenzothiopyrans GENERAL ELECTRIC COMPANY (US) 1976-03-30 US disclosed