SCHEMBL27643287

SCHEMBL27643287

O=Cc1ccc(-n2nnnc2C(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MAPT P10636 3/20 0.44
HPGD P15428 2/20 0.44
HTT P42858 2/20 0.44
CACNA1B Q00975 2/20 0.44
APBA1 Q02410 2/20 0.44
HSP90AA1 P07900 1/20 0.44
KCNJ1 P48048 2/20 0.44
CCR6 P51684 1/20 0.42
ATM Q13315 1/20 0.39
KDM4E B2RXH2 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
MAPK1 P28482 1/20 0.36
NOTUM Q6P988 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468697 0.79 KCNJ1 (0.48) ALDH1A1NPSR1MAPTHPGDHTT
SCHEMBL310917 0.78 ALDH1A1 (0.47) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL5551503 0.78 ALDH1A1 (0.70) ALDH1A1NPSR1MAPTHPGDHTT
SCHEMBL6100503 0.78 ALDH1A1 (0.47) ALDH1A1NPSR1MAPTHPGDHTT
SCHEMBL5549540 0.78 L3MBTL1 (0.52) ALDH1A1NPSR1MAPTHPGDHTT
SCHEMBL4408113 0.78 ALDH1A1 (0.68) ALDH1A1NPSR1MAPTHPGDHTT
SCHEMBL311546 0.77 ERN1 (0.38) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL1971628 0.76 HPGD (0.49) ALDH1A1NPSR1MAPTHPGDHTT
SCHEMBL12513443 0.75 TSHR (0.48) ALDH1A1MAPTHPGDHTTCACNA1B
SCHEMBL4202229 0.75 ATM (0.51) ALDH1A1MAPTHPGDATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100534987-C New method for preparing 2-methoxy-5(5-trifluoromethyl-1H-tetraazo-1-group) benzaldehyde CHENGDU MOLECULAR LAB CO LTD (CN) 2009-09-02 CN claimed
CN-1850810-A New method for preparing 2-methoxy-5(5-trifluoromethyl-1H-tetraazo-1-group) benzaldehyde CHENGDU MOLECULAR LAB CO LTD (CN) 2006-10-25 CN claimed