SCHEMBL27643306

SCHEMBL27643306

[MgH2].[c]1cccc2cccnc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
HTT P42858 3/20 0.41
LMNA P02545 3/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 3/20 0.41
MMP2 P08253 2/20 0.41
CYP3A4 P08684 2/20 0.41
TP53 P04637 2/20 0.41
HSP90AA1 P07900 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GMNN O75496 1/20 0.41
CYP2D6 P10635 1/20 0.41
MMP9 P14780 1/20 0.41
ALOX15 P16050 1/20 0.41
NFKB1 P19838 1/20 0.41
MMP8 P22894 1/20 0.41
CCR1 P32246 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
MMP13 P45452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19695 0.98 TSHR (0.42) TSHRHTTLMNAKDM4EMAPT
SCHEMBL27380184 0.95 TSHR (0.41) TSHRHTTLMNAKDM4EMAPT
SCHEMBL27594643 0.95 TSHR (0.41) TSHRHTTLMNAKDM4EMAPT
SCHEMBL27504674 0.95 TSHR (0.41) TSHRHTTLMNAKDM4EMAPT
SCHEMBL27643304 0.95 TSHR (0.41) TSHRHTTLMNAKDM4EMAPT
SCHEMBL21831938 0.95 TSHR (0.41) TSHRHTTLMNAKDM4EMAPT
SCHEMBL28258823 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL6904790 0.71 KDM4E (0.52) HTTLMNAKDM4EMAPTTP53
SCHEMBL17511921 0.71 LMNA (0.44) TSHRHTTLMNAKDM4EMAPT
SCHEMBL448468 0.71 TSHR (0.39) TSHRHTTLMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100474655-C Organic light-emitting element, method for manufacturing organic light-emitting element, image forming apparatus, and display apparatus MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2009-04-01 CN disclosed
CN-1711804-A Organic light-emitting element, method for manufacturing organic light-emitting element, image forming apparatus, and display apparatus MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2005-12-21 CN disclosed