Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873360 | 0.85 | CA2 (0.56) | CA2CA1HCRTR1HCRTR2NPSR1 | |
| SCHEMBL403938 | 0.82 | CA2 (0.44) | CA2CA1FPR2HCRTR1HCRTR2 | |
| SCHEMBL25031639 | 0.79 | ALDH1A1 (0.51) | HCRTR1HCRTR2NPSR1ALDH1A1GAA | |
| SCHEMBL9925842 | 0.76 | CA2 (0.43) | CA2CA1ALDH1A1GAAPKM | |
| SCHEMBL402028 | 0.76 | CA2 (0.43) | CA2CA1ALDH1A1GAAPKM | |
| SCHEMBL1109256 | 0.75 | TAS1R3 (0.51) | CA2CA1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL9902468 | 0.75 | TAS1R3 (0.51) | CA2CA1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL403937 | 0.75 | TAS1R3 (0.51) | CA2CA1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL12837671 | 0.73 | CA2 (0.43) | CA2CA1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL3819667 | 0.71 | HDAC6 (0.52) | CA2NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102267924-A | Antibacterial agent | — | 2011-12-07 | — | — | CN | disclosed |
| CN-1777577-B | Antibacterial agent | CHIRON CORP | 2011-07-06 | — | — | CN | disclosed |
| CN-1777577-A | Antibacterial agent | CHIRON CORP (US) | 2006-05-24 | — | — | CN | disclosed |